منابع مشابه
Sex determination and the Y chromosome.
Although SRY was first identified 10 years ago, we still know remarkably little about its mode of action or downstream target genes. Recently, potential protein partners have been identified and there has been considerable activity to understand the roles of WT1, SF-1, DAX-1 and SOX9 in gonadogenesis. The emerging picture is one of complex interactions, involving both positive and negative regu...
متن کاملSex Determination: Primitive Y Chromosomes in Fish
Recent analyses of the chromosomal regions that determine male development in sticklebacks and medaka have revealed several features associated with incipient Y chromosome evolution, including suppressed crossing over and the accumulation of repetitive DNA.
متن کاملSex determination in mice: Y and chromosome 17 interactions.
Mice provide material for studies of Y-chromosomal and autosomal sequences involved in sex determination. Eicher and coworkers have identified four subregions in the mouse Y chromosome, one of which corresponds to the Sxr fragment. This fragment demonstrates that only a small portion of the Y is necessary for male sex determination. The mouse Y chromosome also shows variants: the BALB/cWt Y chr...
متن کاملRapid and early determination of sex using trophoblast biopsy specimens and Y chromosome specific DNA probes.
The feasibility of determining sex by analysing deoxyribonucleic acid (DNA) with two probes specific for Y chromosomes was shown using DNA obtained from samples of blood from 30 non-related males and females of different ethnic origin. The DNA was spotted on nitrocellulose filters and hybridised with both a repetitive (P1) and a unique (49f) sequence specific for the human Y chromosome. A stron...
متن کاملComparative In silico Study of Sex-Determining Region Y (SRY) Protein Sequences Involved in Sex-Determining
Background: The SRY gene (SRY) provides instructions for making a transcription factor called the sex-determining region Y protein. The sex-determining region Y protein causes a fetus to develop as a male. In this study, SRY of 15 spices included of human, chimpanzee, dog, pig, rat, cattle, buffalo, goat, sheep, horse, zebra, frog, urial, dolphin and killer whale were used for determine of bioi...
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ژورنال
عنوان ژورنال: Science
سال: 1907
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.25.629.106